Deep learning synthetic computed tomography supported head-and-neck adaptive radiotherapy dose recalculation
Synthetic computed tomography from cone-beam computed tomography achieved a 98.7% gamma pass rate for head-and-neck dose recalculation.
Tag
adaptive-rt
Large target and heart volumes predicted replanning during proton therapy for thoracic cancer
In 180 thoracic proton therapy patients, larger clinical target volume and heart volume independently predicted the need for adaptive replanning.
Weekly synthetic computed tomography identified structure-specific replanning triggers in nasopharyngeal carcinoma
Weekly monitoring identified week 2 triggers for nodal targets and contralateral parotids, with later week 4 triggers for primary targets.
Surface scans showed modest average but substantial individual breast deformation during radiotherapy
Mean treated-breast displacement was 1.6 mm, with larger patient-specific changes near treatment completion and during follow-up.
Mid-treatment tumour shrinkage predicted survival in oropharyngeal cancer
Tumour volume reduction above 40% during radiotherapy was independently associated with improved overall survival in patients with oropharyngeal cancer.
End-to-end test achieved high dosimetric agreement across adaptive platforms
A reusable phantom-based test verified simulation-omitted adaptive workflows on cone-beam computed tomography-guided and magnetic resonance-guided treatment systems.
Monocular surface imaging enables real-time breast dose reconstruction
Patient-specific surface imaging reconstructed breast radiotherapy dose with a 93.8% gamma passing rate and 42-millisecond latency without additional imaging radiation.
Dual-scan conformal cone-beam computed tomography improves target-region image quality
Dynamic collimation improved target-region contrast and signal-to-noise ratio while preserving full-field information without increasing the total photon budget.