cardiac-toxicity - RadOncToday

Higher left anterior descending coronary artery dose was associated with cardiac events after breast radiotherapy

A maximum left anterior descending coronary artery dose of at least 12 Gy was independently associated with higher long-term cardiac risk.

A 40 Gy equivalent dose to at least 18% of the left anterior descending artery was associated with more than twofold risk of cardiac events.

The framework achieved 85.5% external-validation accuracy and reduced estimated review time from 822 hours to 2.3–4.8 hours.