Function-sparing CyberKnife planning reduced dose to deep brain regions without compromising coverage
Adding functional brain regions to CyberKnife optimization reduced dose to multiple structures by roughly 23%–39% while preserving target coverage.
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cyberknife
MR-only CyberKnife planning achieved near-equivalent dosimetry for brain metastases
Synthetic CT reproduced CyberKnife target dosimetry closely and enabled submillimetre translational image guidance, although rotational errors were more variable.
CyberKnife dose models found size-dependent but non-monotonic brain metastasis control
Tumour-size strata showed non-monotonic BED–control relationships, while machine-learning performance remained unvalidated outside a single retrospective centre.
CyberKnife reduced low-dose exposure in left-sided partial-breast irradiation
CyberKnife improved conformity and reduced cardiac, pulmonary, and low-dose exposure, while noncoplanar linac techniques remained clinically acceptable alternatives.