High-dose exposure to the IAS–puborectalis complex tracked with LARS after rectal radiotherapy
Postoperative bowel dysfunction correlated most strongly with high-dose exposure to the internal anal sphincter and puborectalis complex.
Tag
dosimetry
Small photon fields reduced detected Cherenkov signal despite stable dose-linked production
Detected Cherenkov signal per dose fell sharply in small fields, driven mainly by optical transport rather than major changes in intrinsic Cherenkov production.
Smaller sequential brachytherapy applicators improved dose uniformity on curved surfaces
Smaller modular superficial brachytherapy applicators and sequential placement substantially improved dose uniformity, especially for beta-emitting sources.
Modern radiotherapy shifted the accuracy problem from dose calibration to spatial dose delivery
Modern dosimetry can meet historical accuracy requirements, but tighter geometric precision and particle-specific uncertainties increasingly determine treatment accuracy.
Low-dose brain exposure diverged sharply between SRT platforms as metastasis number increased
CyberKnife best contained low-dose spread at high lesion burdens but required substantially longer treatment than faster VMAT strategies.
Higher immune-cell radiation dose was associated with worse breast cancer-specific survival
Each 1-Gy increase in estimated immune-cell dose was associated with 66% higher breast cancer mortality after multivariable adjustment.
Unshielded SunSILICON detector performed reliably for small-field photon dosimetry
The unshielded SunSILICON detector required only modest corrections in small fields, while the shielded version became unreliable below approximately 2 cm.
High-density bolus provided accurate superficial photon dose when air gaps were minimized
A 1 cm high-density bolus overcame 6 MV photon build-up, but a 2 cm air gap reduced small-field skin dose by 21%.
TLD-100 response varied systematically with synchrotron proton dose rate
TLD-100 over-responded below 7 Gy/s and under-responded above 300 Gy/s, despite remaining dose-independent from 3 to 18 Gy.
Tomotherapy improved lung sparing in whole-pleural irradiation for disseminated thymic tumors
Tomotherapy improved target coverage and reduced bilateral lung exposure compared with VMAT and fixed-field IMRT in 20 whole-pleural irradiation cases.
Automated lattice radiotherapy evaluation cut analysis time nearly eightfold
An Eclipse-based tool reduced lattice plan evaluation from 15.4 to 2.0 minutes while maintaining close agreement with manual measurements.
Helium pencil beam commissioning achieved submillimetre range accuracy and robust dose agreement
A scanned helium beamline achieved submillimetre range accuracy and generally ≤3% dose agreement, supporting further translation toward clinical helium therapy.
Modelled actinium-225 delivery reduced glioblastoma clonogens but had limited spatial reach
Convection-enhanced actinium-225 markedly reduced modelled clonogenic survival, but effective coverage extended only about 1.4 cm from each catheter.
Glioblastoma brachytherapy remains limited by non-standardized dosimetry
Modern intracavitary platforms can intensify pericavitary dose immediately after surgery, but standardized patient-specific dosimetry and comparative clinical evidence remain lacking.
Additional PMMA changed mammography multimeter calibration coefficients by up to 42%
Spectral hardening altered multimeter calibration by up to 11% for kerma, 37% for HVL and 42% for voltage.