CTCAE v6.0 grading varied across identical gynecologic radiotherapy toxicity cases
In a small ESTRO poll, subjective and lower-grade adverse events showed substantial disagreement despite shared CTCAE v6.0 definitions.
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gynecologic
Kidney doses below QUANTEC limits still tracked with chronic kidney disease after para-aortic RT
Seven-year stage 3B CKD rose from 0% below 5 Gy mean kidney dose to 26.4% at ≥10 Gy.
PTCOG review maps emerging roles for particle therapy in gynecologic cancers
Carbon ions show the strongest signal in radioresistant gynecologic tumors, while proton evidence centers on adjuvant treatment and reirradiation.
STAMP accelerated gynecologic brachytherapy planning without compromising dosimetry
The standardized workflow generated clinically comparable interstitial brachytherapy plans in a median of 10 minutes versus 28 minutes for manual planning.
Pelvic insufficiency fractures affected nearly one-third after gynecologic IMRT
Pelvic insufficiency fractures occurred in 29.2% of patients, with postmenopause and elevated baseline t-PINP independently predicting risk.
SBRT did not reproduce brachytherapy dose escalation in gynecologic cancers
SBRT provided competitive peripheral coverage in some plans but could not consistently reproduce brachytherapy’s central dose escalation after realistic margins were applied.
Electromagnetic tracking enabled sub-5-mm magnetic resonance imaging–ultrasound guidance in gynecologic brachytherapy
Live magnetic resonance imaging–ultrasound fusion achieved under 4 mm registration accuracy and under 5 mm needle localization in two clinical implants.
Physics-constrained network improved cone-beam computed tomography reconstruction from orthogonal pelvic radiographs
A physics-constrained network reconstructed pelvic cone-beam computed tomography from two simulated radiographs with substantially lower error than generative baselines.