Higher CTV minimum dose predicts local control after separation surgery and spine SBRT
Higher postoperative CTV minimum BED10 was associated with lower local failure after separation surgery and spine SBRT.
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high relevance
High-dose-rate brachytherapy monotherapy achieved durable prostate cancer control
High-dose-rate brachytherapy monotherapy achieved 86% biochemical control at median 13-year follow-up in localized prostate cancer.
Prophylactic cranial irradiation outperformed magnetic resonance imaging surveillance in limited-stage small cell lung cancer
Prophylactic cranial irradiation was associated with longer survival and brain metastasis-free survival than magnetic resonance imaging surveillance.
International consensus supported acute radiation dermatitis scoring tool
An international Delphi panel approved a three-step acute radiation dermatitis tool integrating patient-reported symptoms and clinician assessment.
Partial breast irradiation projected lower secondary lung cancer risk than whole breast irradiation
Partial breast irradiation projected lower lifetime secondary lung cancer risk than whole breast irradiation in Korean early-stage breast cancer cohorts.
Simultaneous integrated boost chemoradiotherapy was linked to better disease-free survival in anal cancer
Simultaneous integrated boost radiotherapy was associated with 96% two-year disease-free survival versus 70% with sequential boost in anal cancer.
Daily adaptive prostate stereotactic body radiotherapy improved target coverage
Daily cone-beam computed tomography-based adaptation improved prostate stereotactic body radiotherapy target coverage, but organ-at-risk dose benefits were inconsistent.
Simulation-free single-fraction radiotherapy was feasible for non-spine metastases
Diagnostic computed tomography-based single-fraction radiotherapy was feasible for selected non-spine palliative metastases, with no grade 3 or higher acute toxicity.
Sandwich chemoradiotherapy showed favorable local control in early natural killer/T-cell lymphoma
Three-year locoregional recurrence-free survival was 90.8%, with most locoregional recurrences occurring within or near the radiation field.
Thyroid complication models showed only moderate long-term validation in head and neck cancer
Existing thyroid complication models showed moderate performance and frequent miscalibration in long-term head and neck cancer survivorship.
Target-prioritized intensity modulated radiotherapy appeared feasible in nasopharyngeal carcinoma near the spinal cord
No radiation myelopathy was observed after target-prioritized intensity modulated radiotherapy for selected nasopharyngeal carcinoma near the spinal cord.
First-line temozolomide and radiotherapy produced similar survival in high-risk low-grade glioma
After 13 years, first-line temozolomide and radiotherapy produced similar progression-free and overall survival across molecularly classified low-grade gliomas.
Severe late toxicity was generally uncommon after prostate radiotherapy in REQUITE
Across 1,760 patients, most grade 3 adverse events remained below 1.5%, although post-prostatectomy urinary incontinence reached 10.2% by eight years.
Higher left anterior descending coronary artery dose was associated with cardiac events after breast radiotherapy
A maximum left anterior descending coronary artery dose of at least 12 Gy was independently associated with higher long-term cardiac risk.
Higher nodal-to-primary tumor volume ratio was associated with distant metastasis in cervical cancer
A nodal-to-primary tumor volume ratio of at least 15% was associated with lower three-year distant metastasis-free survival after extended-field radiotherapy.