Thoracic radiotherapy with atezolizumab increased toxicity in extensive-stage small cell lung cancer
TREASURE found no survival benefit and higher serious toxicity with thoracic radiotherapy added to atezolizumab maintenance.
Tag
immuno-rt
Immuno-Eclipse radiotherapy controlled bulky tumor models through antitumor immunity
Immuno-Eclipse radiotherapy improved bulky tumor control in mice through natural killer and cytotoxic T-cell immunity.
Early stereotactic radiotherapy was associated with longer progression-free survival in pancreatic cancer
Adding early stereotactic body radiotherapy to neoadjuvant chemoimmunotherapy was associated with median progression-free survival of 12.5 versus 6.6 months.
Radiotherapy primes PDL1-targeted radionuclide therapy but splenic uptake limits efficacy
Radiotherapy increased tumor uptake of PDL1-targeted radionuclide therapy, while antibody co-dosing reduced splenic trapping and restored antitumor efficacy in mice.