Locoregional radiotherapy was associated with longer survival in de novo metastatic HNSCC
In de novo metastatic HNSCC, locoregional radiotherapy and first-line immunotherapy were independently associated with longer overall survival.
Tag
immunotherapy
Organ preservation after immunotherapy-based TNT was linked to better bowel function
Organ preservation after immunotherapy-based TNT was associated with better quality of life and markedly lower risk of major bowel dysfunction than TME.
Immunotherapy-based TNT eliminated nodal disease in ypT0–1 rectal tumours
No positive lymph nodes were found in ypT0–1 tumours after immunotherapy-based TNT, supporting further study of local excision.
Perioperative immunotherapy with chemoradiation showed encouraging response in resectable gastric and gastroesophageal junction cancer
A single-arm phase 1/2 trial reported a 39.1% pathologic complete response rate among resected patients, with grade 4 toxicities in 10%.