Posterior tumour drift threatens lung stereotactic ablative radiotherapy target coverage
In free-breathing lung stereotactic ablative radiotherapy, posterior drift exceeded the 4-millimetre margin in 15.7% of patients within 20 minutes.
Tag
lung
Large target and heart volumes predicted replanning during proton therapy for thoracic cancer
In 180 thoracic proton therapy patients, larger clinical target volume and heart volume independently predicted the need for adaptive replanning.
Percussive ventilation enabled imaging and lung stereotactic ablative radiotherapy within one breath-hold
Three of four patients completed final imaging and lung stereotactic ablative radiotherapy within one assisted breath-hold, with only grade 1 adverse events.
Off-axis beam optimization reduced lung dose in posterior lung stereotactic body radiotherapy
Off-axis beam optimization preserved target coverage while reducing lung dose and enabling collision-free beam geometry for posterior lung lesions.
Split inhale–exhale planning reduced rib dose in lung stereotactic body radiotherapy
Splitting eight fractions between inhale and exhale breath-holds reduced maximum rib dose from 67.9 to 33.5 Gy without compromising target coverage.
Robust optimization reduced organ doses in long-course lung radiotherapy
Robust optimization preserved target coverage while reducing lung, heart, esophageal, spinal cord, and estimated immune-cell dose during long-course lung radiotherapy.
Convergent 60 keV photons show cell-dependent biological effectiveness
Convergent 60 keV photons matched orthovoltage radiation and showed comparable or greater biological effectiveness than 6 MV photons, depending on cell type.
Risk-adapted esophagus sparing reduces dose with low severe esophagitis in lung cancer
Risk-adapted esophagus-sparing radiotherapy maintained target coverage, with grade 3 esophagitis in only 1.25% of high-risk patients.