Intrafractional motion frequently exceeded tolerance during multi-target stereotactic radiosurgery
After 66% of couch-angle changes, motion exceeded tolerance, and 0.5-millimetre and 0.5-degree errors reduced near-minimum target dose by 7.6%.
Tag
motion-management
Respiratory motion remained small during postoperative whole-breast radiotherapy.
Mean breast target displacement was below 1.3 mm in every direction, with calculated respiratory margins of approximately 1 mm.
Conventional fractionation substantially reduced gastrointestinal motility–driven interplay in pancreatic proton therapy.
Gastrointestinal motility reduced single-fraction target coverage and broadened organ-at-risk dose ranges, while conventional fractionation substantially attenuated the interplay effect.
Multimodal respiratory tracking enabled real-time voxel-wise anatomical reconstruction during radiotherapy
The patient-specific framework outperformed three comparison methods and reconstructed respiratory anatomy in 15.6 milliseconds per frame.
Hybrid respiratory gating mitigated interplay in spot-scanning proton therapy
Hybrid phase-amplitude gating restored dose agreement during regular motion, while irregular breathing increased treatment time and produced inconsistent accuracy.
Split inhale–exhale planning reduced rib dose in lung stereotactic body radiotherapy
Splitting eight fractions between inhale and exhale breath-holds reduced maximum rib dose from 67.9 to 33.5 Gy without compromising target coverage.
Failure analysis identifies target definition and motion management as key risks in stereotactic arrhythmia radioablation
Multimodal registration, motion management, and arrhythmia substrate definition were the highest-risk steps in stereotactic arrhythmia radioablation.
Machine-specific timing model improves synchrotron proton spot delivery prediction
Measured multi-energy extraction characteristics enabled accurate delivery-time prediction across 605 clinical proton fields, supporting more reliable interplay simulations.