Extratumoral perineural invasion predicted poorer survival, while microscopic versus macroscopic extranodal extension did not meaningfully separate outcomes.
An MRI and pathology-based model identified a poor-risk oral tongue cancer group in which postoperative radiotherapy was associated with improved survival.
Smaller base-of-tongue volume was associated with prolonged feeding-tube dependence after radiotherapy for oral cavity squamous cell carcinoma.
Postoperative conventional radiotherapy caused fewer head-and-neck symptoms and dominated preoperative accelerated radiotherapy in the five-year cost-utility analysis.