Radiotherapy was not associated with longer survival in breast cancer leptomeningeal disease
In 232 women with breast cancer leptomeningeal disease, radiotherapy was not associated with longer overall survival, while systemic therapy was.
Tag
palliative
Simulation-free CBCT workflow enabled urgent radiotherapy within about two hours
The OSCAR workflow delivered the first urgent or palliative fraction without planning CT in approximately 1 hour 50 minutes.
Re-irradiation was associated with longer survival after pediatric diffuse midline glioma progression
COMPPARE enrolled 2,524 patients from 51 institutions in 52 months, with Black participation reaching 16% of the cohort.
Bone metastasis trials need treatment-intent endpoints beyond pain response
Pain should remain central for symptomatic disease, but prevention, function, local control and skeletal events require separate standardized endpoints.
Higher-BED palliative radiotherapy improved symptoms in rectal cancer
BED >37.5 Gy improved symptomatic control, while 6-month local control remained 46% in frail, elderly, or metastatic rectal cancer.
Dutch survey found wide variation in radiotherapy for unresectable recurrent rectal cancer
Dutch radiation oncologists reported substantial variation in dose, delineation, and follow-up for unresectable locally recurrent rectal cancer.
Machine learning stratified survival after palliative radiotherapy for bone metastases
A decision tree model identified interleukin-8, hemoglobin, and lymphocyte count as key survival predictors after palliative radiotherapy.
Single-fraction radiotherapy matched multifraction treatment for malignant bone tumor pain
Single-fraction external beam radiotherapy provided similar pain relief to multifraction treatment in this meta-analysis of malignant bone tumor pain.
Simulation-free single-fraction radiotherapy was feasible for non-spine metastases
Diagnostic computed tomography-based single-fraction radiotherapy was feasible for selected non-spine palliative metastases, with no grade 3 or higher acute toxicity.