No lung subregion strategy clearly improved radiation pneumonitis prediction
Whole-lung, physical-dose and BED3 models performed similarly externally, with the best complete-model AUC only 0.684 and inadequate calibration.
Whole-lung, physical-dose and BED3 models performed similarly externally, with the best complete-model AUC only 0.684 and inadequate calibration.
A hybrid peri-tumoural CT model achieved an external AUC of 0.828 for predicting grade 2 or higher radiation pneumonitis.
A randomized phase II trial will test whether intravenous tetrandrine reduces grade 2 or higher lung injury from 25% to 10%.
A mean lung dose threshold of 12.70 grays strongly separated patients who developed radiation pneumonitis after adjuvant breast radiotherapy.
A center-specific federated learning model predicted grade 2 or higher radiation pneumonitis with stable cross-dataset performance.