Most pT4 laryngeal cancer patients started postoperative RT beyond six weeks
Only 21% started PORT within 42 days after laryngectomy, while each additional week of delay was associated with 3.7% higher mortality.
Only 21% started PORT within 42 days after laryngectomy, while each additional week of delay was associated with 3.7% higher mortality.
Among 34 postoperative oral cavity cases, local failures occurred at or near the flap-native interface, with no recurrence inside the flap.
Wound dehiscence occurred in 78% of extensively involved keloid sites versus 5% of simple lesions after surgery and postoperative RT.
Four patients completed 54 Gy after airway reconstruction without graft-related toxicity or local recurrence during early follow-up.
Across 12 retrospective studies, radiotherapy achieved 67–100% fistula-control rates, often with cumulative doses of only a few gray.
Extratumoral perineural invasion predicted poorer survival, while microscopic versus macroscopic extranodal extension did not meaningfully separate outcomes.
Weekly cisplatin remained non-inferior to three-weekly cisplatin at five years in postoperative high-risk head and neck chemoradiotherapy.