Larger bladder geometry was linked to lower planned bladder dose in prostate radiotherapy
Larger bladder volume was strongly associated with lower planned bladder dose in a static five-fraction prostate radiotherapy analysis.
Tag
prostate
High lactate dehydrogenase-5 and low lymphocyte infiltration identified higher relapse risk after prostate radiotherapy
Combined high lactate dehydrogenase-5 expression and low tumor-infiltrating lymphocyte density independently identified higher biochemical relapse risk after prostate radiotherapy.
Severe late toxicity was generally uncommon after prostate radiotherapy in REQUITE
Across 1,760 patients, most grade 3 adverse events remained below 1.5%, although post-prostatectomy urinary incontinence reached 10.2% by eight years.
Knowledge-based prostate planning transfers across fractionation regimens with comparable plan quality
A conventional-fractionation model produced clinically acceptable moderately hypofractionated prostate plans, with comparable overall quality and slightly reduced target homogeneity.
Single-fraction prostate radiotherapy achieved 92.9% three-year biochemical relapse-free survival
A single 19-Gy fraction achieved 92.9% three-year biochemical relapse-free survival with limited grade 2 gastrointestinal and genitourinary toxicity.