Causal modeling suggested elevated proton RBE for mandibular osteoradionecrosis
Causal modeling estimated mandibular proton RBE at 1.61, 1.30 and 1.13 at 40, 50 and 60 GyRBE, respectively
Causal modeling estimated mandibular proton RBE at 1.61, 1.30 and 1.13 at 40, 50 and 60 GyRBE, respectively
Different carbon-ion RBE models can assign substantially different biological doses to the same absorbed-dose distribution, requiring context-specific translation.
Proton therapy produced greater CT-detected lung changes than photons despite lower lung dose and no increase in clinical pulmonary toxicity.
A translational review proposes shared reporting and quality-assurance principles for model-dependent biological dose in proton, carbon-ion and boron neutron capture therapy.