Non-endemic nasopharyngeal cancer showed similar locoregional and distant failure rates
Five-year overall survival was 71%, with most distant failures occurring during the first three years after treatment.
Tag
Retrospective
Extensive coronary calcification on breast RT planning CT predicted ischemic heart disease
All six ischemic events occurred in patients with extensive coronary calcification on breast RT simulation CT, versus none with absent or mild calcification.
Simulation-free vaginal brachytherapy produced low five-year recurrence in high-intermediate-risk endometrial cancer
Five-year vaginal recurrence was 3.6% without verification imaging, versus 1.6% reported in the separate PORTEC-4a brachytherapy cohort.
Progesterone exposure was associated with visual deficits in women with meningioma
Unopposed progesterone use was associated with eightfold higher odds of tumor-related visual deficit among women referred for meningioma radiotherapy.
Most glioblastoma recurrences clustered within 10 mm of the original GTV
In 201 recurrent glioblastomas, 80% required no more than 10.4 mm expansion to encompass 80% of recurrence volume.
Internal mammary node response may reveal occult disease in early breast cancer
Nearly 40% of visible internal mammary nodes regressed after chemotherapy, including 22% in patients without axillary nodal disease.
Radiotherapy was not associated with longer survival in breast cancer leptomeningeal disease
In 232 women with breast cancer leptomeningeal disease, radiotherapy was not associated with longer overall survival, while systemic therapy was.
Radiotherapy may offset the survival disadvantage of perineural invasion in cutaneous head and neck cancer
PNI-positive patients without radiotherapy had worse survival, while those receiving radiotherapy had outcomes comparable to patients without PNI.
Extratumoral perineural invasion predicted worse outcomes after postoperative oral cavity radiotherapy
Extratumoral perineural invasion predicted poorer survival, while microscopic versus macroscopic extranodal extension did not meaningfully separate outcomes.
Danish head and neck risk model generalized to an Australian radiotherapy cohort
The model retained moderate discrimination for recurrence and metastasis, but predicted non-cancer death less reliably, especially in older patients.
Carboplatin-paclitaxel showed comparable outcomes in cisplatin-ineligible head and neck cancer
Retrospective outcomes with carboplatin-paclitaxel were not significantly different from cisplatin, supporting its use when cisplatin is contraindicated.
Higher pretreatment LMR weakly predicted cervical tumour shrinkage after EBRT
Pretreatment lymphocyte-to-monocyte ratio was independently associated with cervical tumour shrinkage, but its standalone discrimination was poor.
Smaller base-of-tongue volume was associated with prolonged feeding-tube dependence
Smaller base-of-tongue volume was associated with prolonged feeding-tube dependence after radiotherapy for oral cavity squamous cell carcinoma.
Medial retropharyngeal nodes were involved in 2.95% of non-endemic nasopharyngeal cancers
Medial retropharyngeal nodes were involved in 2.95% of German cases, but no recurrence occurred among patients whose elective volume omitted the region.
Gamma Knife radiosurgery showed durable control in postoperative papillary craniopharyngioma
Gamma Knife radiosurgery achieved 73.53% 5-year progression-free survival in a small postoperative papillary craniopharyngioma cohort.