CBCT adaptive RT is increasingly automated, but clinical decision-making still needs human oversight
AI can automate major components of CBCT-guided adaptation, but validated triggers, end-to-end QA and patient-outcome evidence remain limited.
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review
Spectral CT could strengthen RT planning and adaptation, but clinical validation still lags
Spectral CT adds quantitative tissue information across planning, particle range estimation and adaptive imaging, but prospective outcome evidence remains limited.
Single-fraction SBRT has strongest curative evidence in peripheral lung and kidney tumors
ESTRO’s review supports selected single-fraction SBRT applications while highlighting major evidence and toxicity gaps in abdominal tumors.
Deep-learning metal artifact reduction achieved sub-3% dose errors in head-and-neck radiotherapy
Retrospective DL-MAR studies achieved dose errors below 3%, but no prospective clinical validation has yet been reported.
Most breast cancer RT appears safe with ADCs, but T-DM1 raises concern after brain SRS
Across 3,817 patients, severe toxicity was uncommon with RT plus ADCs, except for a radiation-necrosis signal with intracranial RT and T-DM1.
Living ESTRO/OligoCare review maps safety signals for SRT with modern systemic therapy
Across 7,694 patients, most SRT–systemic therapy combinations appeared tolerable, but BRAF/MEK inhibitors, T-DM1 and liver SRT showed caution signals.
Personalized RT strategies are moving locally advanced NSCLC beyond the PACIFIC template
Modern LA-NSCLC RT is shifting toward selective escalation, de-escalation and organ sparing, increasingly guided by patient risk and tumor biology.
SABR controls oligometastatic breast lesions well, but systemic benefit remains uncertain
SABR achieved 92.5% one-year local control in oligometastatic breast cancer, while pooled randomized evidence did not definitively establish a PFS benefit.
New framework defines core competencies for contemporary brain brachytherapy
The framework emphasizes multidisciplinary selection, source geometry, imaging, postimplant dosimetry, QA and radiation safety for modern intracranial Cs-131 brachytherapy.
Experts define the roadmap for clinical upright gantry-less radiotherapy
Upright gantry-less RT could reduce system complexity and improve access, but imaging, immobilization and limited clinical evidence remain major barriers.
COG highlights major gaps in radiation care for adolescents and young adults
AYA patients face distinct radiation-related late effects and psychosocial challenges, yet age-specific dose constraints and prospective outcome data remain scarce.
Late chest-wall pain affected one-third of patients after breast radiotherapy
Across 5,509 evaluable patients, 34% developed late chest-wall pain, although definitions and reported risk factors varied substantially.
Virtual reality often reduced anxiety and pain during breast cancer care
Across 14 studies, 9 of 11 anxiety studies and 3 of 5 pain studies reported significant improvement with virtual reality.
SGRT-assisted DIBH reduced heart and LAD dose in left-sided breast radiotherapy
Across 52 studies, SGRT-assisted DIBH reduced mean heart dose by 1.21 Gy and LAD dose by 7.05 Gy versus free breathing.
Aggressive concurrent hypofractionation increased fatal toxicity in unresectable stage II–III NSCLC
Across 26 studies, fatal toxicity clustered when BED10 >100 Gy was delivered to the whole tumor with concurrent platinum chemotherapy.