Prospective prostate reirradiation studies reported generally acceptable toxicity, but target volumes, dose schedules and organ constraints varied substantially.
Circadian dysregulation could impair DNA repair and haematopoietic control after radiation exposure, but direct evidence linking it to acute myeloid leukaemia is lacking.
Rigid couch correction cannot fully resolve regional posture mismatch, immobilization failure or progressive anatomical change during head and neck radiotherapy.
A translational review proposes shared reporting and quality-assurance principles for model-dependent biological dose in proton, carbon-ion and boron neutron capture therapy.
Only 12 eligible studies were found, with inconsistent methods and assumptions that limited meaningful comparison of particle therapy costs.
DEGRO supports ultrahypofractionation for low- to intermediate-risk prostate cancer, with comparable control but increased late genitourinary toxicity in selected patients.
Nearly one-third of lung SBRT studies counted failures beyond the treated tumor as local events, limiting comparison of reported control rates.
This systematic review found that optimal radiotherapy-immunotherapy sequencing depends on the immune mechanism being targeted.
Single-fraction external beam radiotherapy provided similar pain relief to multifraction treatment in this meta-analysis of malignant bone tumor pain.
After stereotactic body radiation therapy for hepatocellular carcinoma, magnetic resonance response evolved over months, making early enhancement alone unreliable.
Carbon fiber-reinforced polyetheretherketone implants consistently reduced imaging artifacts and dosimetric uncertainty versus titanium, but clinical outcome evidence remains limited.
Most studies used heterogeneous, poorly reproducible cosmetic assessment methods, limiting comparisons between radiotherapy techniques and supporting development of a validated standard.
Bone marrow-sparing planning reduced pelvic marrow dose, but heterogeneous evidence did not confirm a consistent reduction in hematologic toxicity.