Kidney proton SBRT needed a larger superior–inferior robustness margin
Kidney proton SBRT modeling supported 4-mm superior–inferior and 3-mm lateral/anterior–posterior positioning uncertainty with intrafraction repositioning.
Tag
robust-optimization
Robust optimization minimized lung-dose trade-offs in carbon-ion planning for stage I NSCLC
Robust optimization improved target coverage with less lung-dose penalty than margin expansion, while density override was particularly useful for solid tumors.
Photon robust optimization remains technically promising but poorly standardized
Robust photon planning usually improved uncertainty-resistant target coverage, but modelling, evaluation, and reporting varied substantially across the literature.
Robust IMPT modestly reduced organ-at-risk dose in five-fraction prostate proton therapy
SFUD and robust IMPT maintained target coverage under uncertainty, while IMPT modestly reduced rectal and bladder dose.
Direct cord robust optimization preserved target coverage near the spinal cord
In ten paraspinal chordoma plans, direct cord robust optimization improved coverage and robustness while maintaining acceptable spinal cord doses.
Robust optimization reduced organ doses in long-course lung radiotherapy
Robust optimization preserved target coverage while reducing lung, heart, esophageal, spinal cord, and estimated immune-cell dose during long-course lung radiotherapy.