Higher minimum target dose improved local control after repeat spine SBRT
After repeat spine SBRT, 12-month local failure was 6% with Dmin ≥28 Gy EQD2 versus 36% below that level.
Tag
spine-metastases
Proton hypofractionation achieved durable control in heavily reirradiated spine metastases
Proton hypofractionation produced 10% one-year local failure despite extensive prior irradiation, with grade 3 toxicity confined to multiply reirradiated patients.
Omitted guideline-recommended sectors drove local failure after sacral SBRT
Seventy-three percent of failures after nonadherent sacral contouring involved sectors that guidelines recommended including in the clinical target volume.
Protons reduced spinal cord and bowel dose in single-fraction spine SBRT plans
Proton plans preserved 20-Gy target coverage while reducing spinal cord, oesophageal, lung, and bowel dose compared with photon VMAT.
Spine proton ablative radiotherapy achieved 74% two-year local control in selected patients
Spine proton ablative radiotherapy achieved 74% local control at one and two years, with no radiation myelopathy in a reirradiation-enriched cohort.
Higher CTV minimum dose predicts local control after separation surgery and spine SBRT
Higher postoperative CTV minimum BED10 was associated with lower local failure after separation surgery and spine SBRT.
Carbon fiber-reinforced implants may reduce uncertainty in postoperative spine stereotactic body radiotherapy
Carbon fiber-reinforced polyetheretherketone implants consistently reduced imaging artifacts and dosimetric uncertainty versus titanium, but clinical outcome evidence remains limited.