No tested head phantom fully met cranial synthetic CT QA criteria
Skull-equivalent anatomy improved synthetic CT performance, but none of ten tested head phantoms satisfied all geometric, HU and dosimetric criteria.
Tag
synthetic-ct
CBCT-derived synthetic CT predicted head and neck replanning with 92% sensitivity and specificity
DART predicted clinically triggered head and neck adaptation with 92% sensitivity and specificity using a unified 2-Gy dosimetric threshold.
Real-world brain MR-only implementation exposed frequent synthetic CT artifacts
Synthetic CT artifacts were common during brain MR-only implementation, highlighting workflow QA and patient-selection issues not captured by controlled validation.
Commercial AI synthetic CT showed good soft-tissue agreement but important high-density failures
AI synthetic CT preserved soft-tissue HU and geometry well, while bone, air interfaces and implanted devices remained important failure modes.
Acuros XB increased synthetic CT dose differences but remained clinically acceptable
Acuros XB was more sensitive than AAA to synthetic CT discrepancies, but target-dose differences remained small in prostate and glioma plans.
Bidirectional GAN preserved CT numbers and dose accuracy in head-and-neck planning CT
BiHU-GAN generated synthetic contrast and non-contrast CT with high contour agreement and at least 95% gamma pass rates at 2%/2 mm.
Magnetic resonance-only simulation supported prostate magnetic resonance-guided stereotactic body radiotherapy
Magnetic resonance-only prostate simulation achieved 96.80% local gamma agreement using synthetic computed tomography for dose calculation.
Virtual magnetic resonance linear accelerator improved adaptive pelvic lymph node radiotherapy dosimetry
Daily magnetic resonance-informed adaptation increased target coverage by 14% and reduced bowel dose by 7% for pelvic lymph node metastases.
Deep learning synthetic computed tomography supported head-and-neck adaptive radiotherapy dose recalculation
Synthetic computed tomography from cone-beam computed tomography achieved a 98.7% gamma pass rate for head-and-neck dose recalculation.
Weekly synthetic computed tomography identified structure-specific replanning triggers in nasopharyngeal carcinoma
Weekly monitoring identified week 2 triggers for nodal targets and contralateral parotids, with later week 4 triggers for primary targets.