Respiratory motion remained small during postoperative whole-breast radiotherapy.
Mean breast target displacement was below 1.3 mm in every direction, with calculated respiratory margins of approximately 1 mm.
Mean breast target displacement was below 1.3 mm in every direction, with calculated respiratory margins of approximately 1 mm.
Gastrointestinal motility reduced single-fraction target coverage and broadened organ-at-risk dose ranges, while conventional fractionation substantially attenuated the interplay effect.
The patient-specific framework outperformed three comparison methods and reconstructed respiratory anatomy in 15.6 milliseconds per frame.
Live magnetic resonance imaging–ultrasound fusion achieved under 4 mm registration accuracy and under 5 mm needle localization in two clinical implants.
Weekly monitoring identified week 2 triggers for nodal targets and contralateral parotids, with later week 4 triggers for primary targets.
K-means matched hybrid optimization for margin volume while reducing median computation time from 306.9 seconds to 0.19 seconds.
98.98% of virtual contrast-enhanced MRI scans were rated suitable for diagnosis, and 92.33% for tumor delineation.
A physics-constrained network reconstructed pelvic cone-beam computed tomography from two simulated radiographs with substantially lower error than generative baselines.
Respiratory gating more than halved cranio-caudal motion, while motion-related target-dose deviations largely diminished after accumulation across more than three fractions.
No single patient-specific quality assurance method covered all stereotactic radiotherapy risks, supporting combinations of measurement, independent calculation, imaging, and monitoring.
Mean treated-breast displacement was 1.6 mm, with larger patient-specific changes near treatment completion and during follow-up.
A 3D-printed jig delivered approximately uniform iridium-192 tumor dose, delayed tumor growth, and caused no observable short-term radiation toxicity in mice.
Hybrid phase-amplitude gating restored dose agreement during regular motion, while irregular breathing increased treatment time and produced inconsistent accuracy.
Off-axis beam optimization preserved target coverage while reducing lung dose and enabling collision-free beam geometry for posterior lung lesions.
Robust optimization preserved target coverage while reducing lung, heart, esophageal, spinal cord, and estimated immune-cell dose during long-course lung radiotherapy.