Robust IMPT modestly reduced organ-at-risk dose in five-fraction prostate proton therapy
SFUD and robust IMPT maintained target coverage under uncertainty, while IMPT modestly reduced rectal and bladder dose.
Tag
technical-relevance
GPT-4.1 retrieved TrueBeam troubleshooting history but retained safety risks
A retrieval-augmented GPT-4.1 chatbot rapidly surfaced previous TrueBeam faults, but procedural, role-definition and safety errors remained.
Interpretable autoencoder detected anomalous IMRT plans with high discrimination
An autoencoder identified anomalous IMRT plans with an area under the curve of 0.98 and explained which parameters drove each alert.
In-beam PET enabled real-time radioactive ion beam range adaptation in mice
Radioactive carbon-11 beams enabled PET-guided range adjustment during irradiation, with biological outcomes matching insufficient, optimal and excessive beam penetration.
Brain metastasis contouring variability depended on lesion and MRI factors
Brain metastasis contours showed generally high agreement, although lesion volume, oedema and magnetic resonance imaging field strength influenced variability.
Dose reporting mode affected spine SBRT audit results
A national end-to-end audit found acceptable spine stereotactic radiotherapy accuracy but systematic differences between dose-reporting conventions.
High geometric agreement did not guarantee physician acceptance of AI contours
Thoracic AI contours showed strong geometric and dosimetric agreement, but physicians still rejected some heart and oesophageal contours.
Deep learning reconstructed one-minute gated CBCT for pancreatic radiotherapy
Deep-learning reconstruction produced pancreatic gated cone-beam computed tomography comparable with conventional imaging while reducing estimated acquisition time and imaging dose.
A 4.5 mm margin covered most intrafraction small-bowel motion during MR-guided radiotherapy
A 4.5 mm isotropic margin covered most observed small-bowel occupancy despite craniocaudal displacements exceeding 20 mm in some patients.
CT imaging features improved local and distant control prediction in nasopharyngeal carcinoma
Planning CT features added prognostic information for local and distant control but did not significantly improve overall or progression-free survival prediction.
Upright carbon ion plans matched supine dosimetry for prostate cancer
Upright carbon ion treatment plans achieved target coverage, organ sparing and simulated robustness comparable with conventional supine plans.
Automated framework linked 99.76% of radiotherapy planning and delivery datasets
The framework linked complete planning and delivery data for 13,871 plans with 99.76% success across two clinics.
Fraction 15 was optimal for one-time offline replanning in head and neck proton therapy
A single offline replan at fraction 15 captured most achievable dosimetric benefit in simulated head and neck proton therapy.
Surface-contacted 3D bolus plus MLC reduced proton PBS lateral penumbra
Surface-contacted 3D boluses generally narrowed lateral penumbra and reduced surrounding dose versus a nozzle-mounted range shifter in proton PBS.
Multidisciplinary radiopharmaceutical dosimetry changed management in one-third of selected patients
In 19 high-risk patients receiving 177Lu-PSMA-617, post-cycle 1 dosimetry changed management in 32%, prompting five activity reductions and one delay.