Pelvis-inclusive SBRT reduced acute gastrointestinal toxicity in high-risk prostate cancer
Once-weekly prostate-and-pelvis SBRT reduced acute gastrointestinal toxicity versus conventional IMRT without significantly increasing genitourinary toxicity.
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trial
NEOTRAC shortened treatment duration without improving pCR in HER2-positive inoperable breast cancer
Concurrent neoadjuvant radiotherapy shortened treatment duration but did not improve pathological complete response or survival.
Fat necrosis remained low after single-fraction stereotactic partial breast irradiation
Single-fraction GammaPod partial breast irradiation produced 12.1% fat necrosis and 4.1% symptomatic fat necrosis in a phase 2 trial.
Thoracic radiotherapy with atezolizumab increased toxicity in extensive-stage small cell lung cancer
TREASURE found no survival benefit and higher serious toxicity with thoracic radiotherapy added to atezolizumab maintenance.
Single-fraction ultrahigh dose-rate proton therapy showed early safety in thoracic metastases
Single-fraction proton treatment produced pain responses without grade 2 or higher related toxicity in 10 patients with thoracic bone metastases.