Postoperative high-dose RT achieved strong local control in lacrimal gland adenoid cystic carcinoma
After surgery plus 66–70 Gy, only one of six patients recurred locally, while half developed distant metastases.
After surgery plus 66–70 Gy, only one of six patients recurred locally, while half developed distant metastases.
Diagnostic CT-based VMAT preserved PTV D95 at 99.6% of planned dose across 30 palliative bone RT plans.
Seven patients completed 60 Gy with no recurrences, grade ≥3 skin toxicity, fibrosis, cartilage necrosis, or nasal contour deformation at early follow-up.
Four patients completed 54 Gy after airway reconstruction without graft-related toxicity or local recurrence during early follow-up.
Double-arc VMAT was slightly more robust, but single-arc planning achieved clinically comparable dosimetry with simulated bilateral hip prostheses.
Jaw-partitioned VMAT improved dose gradients and peak-to-valley separation in GRID and lattice plans, but approximately doubled monitor units.
Obturator nodes received about 75% of the prescribed bladder dose incidentally, with similar regional exposure from VMAT and fixed-field IMRT.
Restricting deep VMAT apertures reduced heart and ipsilateral lung exposure across three linacs while maintaining comprehensive breast and nodal coverage.
VMAT exposed less circulating blood than IMRT, but modeled immune-cell depletion differed by only one percentage point after 30 fractions.
VMAT-TBI achieved 96.6% mean PTV D95 while keeping mean lung and kidney doses below 9 Gy.
Patient-specific stents improved tongue and parotid stability and were associated with substantially less hearing loss, dysphagia and dysgeusia.
uTPS generated Halcyon VMAT plans with generally comparable dosimetry to Eclipse and greater than 97% gamma passing rates.
Twelve VMAT lattice courses produced 65% median tumor shrinkage and no local progression during short follow-up in bulky hepatocellular carcinoma.
In eight bulky tumor sites, flattening-filter VMAT lattice radiotherapy produced 75% symptom relief with no grade 3 or higher acute toxicity.
AI-assisted planning cut average planning time from about two hours to 30 minutes, but three of 12 plans required manual hotspot correction.