Hemithoracic radiotherapy after surgery achieved durable control in pleural thymoma
After surgery and 14 Gy hemithoracic radiotherapy, five-year progression-free survival was 50.8% with only one grade 3 pneumonitis.
Latest research
Search the archiveLow-dose radiotherapy showed very low in-field solid cancer incidence after musculoskeletal treatment
Only three in-field solid malignancies occurred among 4,699 patients, while marrow-adjacent irradiation was associated with slightly more hematologic malignancies.
CBCT dose changes predicted adaptive radiotherapy benefit better than volume changes
Week-three CBCT dose changes predicted head and neck adaptive radiotherapy benefit with AUC 0.78 versus 0.54 using volume changes.
Salvage HDR brachytherapy had low severe toxicity but limited five-year biochemical control
Five-year PSA progression-free survival was 24.8% after two-fraction salvage HDR brachytherapy without androgen deprivation, despite low severe toxicity.
Overlap-adapted dose reduction lowered temporal lobe injury in T4 nasopharyngeal cancer
Reducing the PTV–temporal lobe overlap dose to 66 Gy lowered five-year radiographic temporal lobe injury from 36.2% to 23.2%.
Persistent internal mammary nodes on MRI identified patients associated with benefit from boost
Internal mammary node boost was associated with better disease-free survival only when MRI showed residual nodal disease after neoadjuvant therapy.
Lithium mouthwash reduced severe oral mucositis during head and neck radiotherapy
Lithium mouthwash reduced severe oral mucositis from 52.1% to 34.2% in a randomized phase II head and neck radiotherapy trial.
Yttrium-90 radioembolization produced durable hepatic responses in SDH-deficient GIST
Yttrium-90 radioembolization achieved 67% objective response and 100% disease control in 12 patients with SDH-deficient GIST liver metastases.
Most salvage prostate radiotherapy plans met SPPORT and RADICALS-HD dose constraints
Most multicenter salvage prostate radiotherapy plans met SPPORT and RADICALS-HD organ constraints, with smaller bladder volumes linked to more violations.
Smaller sequential brachytherapy applicators improved dose uniformity on curved surfaces
Smaller modular superficial brachytherapy applicators and sequential placement substantially improved dose uniformity, especially for beta-emitting sources.
Deep learning proton plans were clinically accepted for all 78 oropharyngeal patients
All 78 deep learning-generated IMPT plans were clinically accepted, with comparable or lower organ doses than manual benchmark plans.
REQUITE revealed persistent toxicity and sex-specific symptom patterns after lung radiotherapy
Prospective REQUITE data showed substantial pulmonary toxicity after lung radiotherapy, with several sex-specific differences in symptoms and recovery.
Gamma Knife and LINAC radiosurgery produced similar vestibular schwannoma outcomes
Gamma Knife and LINAC radiosurgery produced similarly high control and low new neurologic symptoms in 85 vestibular schwannoma patients.
Causal modeling suggested elevated proton RBE for mandibular osteoradionecrosis
Causal modeling estimated mandibular proton RBE at 1.61, 1.30 and 1.13 at 40, 50 and 60 GyRBE, respectively
Age and comorbidity identified poor prognosis in elderly patients receiving esophageal chemoradiotherapy
Patients aged ≥75 years with CIRS-G ≥7 had median overall survival of 16 months after definitive chemoradiotherapy.