Low-dose radiotherapy produced durable benefit in refractory plantar fasciitis
Low-dose radiotherapy produced sustained pain, function and quality-of-life improvement after conservative treatment and shock-wave therapy had failed.
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FLASH preserved mitochondrial function in non-tumorigenic pancreatic models
FLASH spared mitochondrial integrity in non-tumorigenic pancreatic models while producing tumour effects comparable with conventional-dose-rate irradiation.
SPPORT intensification did not worsen long-term quality of life
Short-term androgen deprivation impaired early sexual and hormonal quality of life, but treatment-arm differences were not clinically significant at five years.
Circadian disruption may modify radiation-induced acute myeloid leukaemia risk
Circadian dysregulation could impair DNA repair and haematopoietic control after radiation exposure, but direct evidence linking it to acute myeloid leukaemia is lacking.
Head and neck positioning management should extend beyond couch correction
Rigid couch correction cannot fully resolve regional posture mismatch, immobilization failure or progressive anatomical change during head and neck radiotherapy.
Late radiation necrosis after stereotactic radiosurgery temporally associated with COVID-19 vaccination
A case report describes pathology-confirmed late radiation necrosis after stereotactic radiosurgery, with radiographic progression temporally associated with repeated COVID-19 vaccination.
Review proposes harmonized reporting of biological dose across particle therapies
A translational review proposes shared reporting and quality-assurance principles for model-dependent biological dose in proton, carbon-ion and boron neutron capture therapy.
A 4.5 mm margin covered most intrafraction small-bowel motion during MR-guided radiotherapy
A 4.5 mm isotropic margin covered most observed small-bowel occupancy despite craniocaudal displacements exceeding 20 mm in some patients.
CT imaging features improved local and distant control prediction in nasopharyngeal carcinoma
Planning CT features added prognostic information for local and distant control but did not significantly improve overall or progression-free survival prediction.
Upright carbon ion plans matched supine dosimetry for prostate cancer
Upright carbon ion treatment plans achieved target coverage, organ sparing and simulated robustness comparable with conventional supine plans.
Mean lung dose strongly predicted pneumonitis after adjuvant breast radiotherapy
A mean lung dose threshold of 12.70 grays strongly separated patients who developed radiation pneumonitis after adjuvant breast radiotherapy.
Higher-dose iodine-125 brachytherapy was associated with longer survival in recurrent glioblastoma
Iodine-125 doses of 140–160 grays were associated with longer median survival than 120–140 grays in recurrent glioblastoma.
Smaller base-of-tongue volume was associated with prolonged feeding-tube dependence
Smaller base-of-tongue volume was associated with prolonged feeding-tube dependence after radiotherapy for oral cavity squamous cell carcinoma.
Automated framework linked 99.76% of radiotherapy planning and delivery datasets
The framework linked complete planning and delivery data for 13,871 plans with 99.76% success across two clinics.
FDG-PET-guided dose escalation did not improve control in advanced oropharyngeal and laryngopharyngeal cancers
Escalating metabolically active disease to 73.5 Gy did not improve locoregional control, disease-free survival, or overall survival versus 66 Gy.