High-dose-rate brachytherapy monotherapy achieved durable prostate cancer control
High-dose-rate brachytherapy monotherapy achieved 86% biochemical control at median 13-year follow-up in localized prostate cancer.
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Search the archiveProphylactic cranial irradiation outperformed magnetic resonance imaging surveillance in limited-stage small cell lung cancer
Prophylactic cranial irradiation was associated with longer survival and brain metastasis-free survival than magnetic resonance imaging surveillance.
Deep learning reduced head and neck auto-segmentation editing, but user variability persisted
Deep learning auto-segmentation reduced editing, but both minimal and excessive manual edits were associated with lower clinical acceptability.
Machine learning stratified survival after palliative radiotherapy for bone metastases
A decision tree model identified interleukin-8, hemoglobin, and lymphocyte count as key survival predictors after palliative radiotherapy.
Artificial intelligence planning generated clinically acceptable whole-brain radiotherapy plans
Artificial intelligence planning produced clinically acceptable whole-brain radiotherapy plans in 14 of 15 independent test cases.
Same-day hyaluronic acid spacer reduced rectal dose in prostate brachytherapy
Same-day hyaluronic acid rectal spacer placement reduced rectal dose while preserving ultrasound-based prostate brachytherapy planning.
Artificial intelligence surrogate estimated coronary artery dose in lung stereotactic body radiotherapy
An artificial intelligence coronary artery surrogate strongly correlated with manual dose metrics in simulated lung stereotactic body radiotherapy.
Tumor treating field arrays increased surface dose during photon radiotherapy
Tumor treating field arrays caused substantial surface dose enhancement and measurable dose attenuation during 6-megavolt photon irradiation.
Immuno-Eclipse radiotherapy controlled bulky tumor models through antitumor immunity
Immuno-Eclipse radiotherapy improved bulky tumor control in mice through natural killer and cytotoxic T-cell immunity.
Gamma Knife radiosurgery showed durable control in postoperative papillary craniopharyngioma
Gamma Knife radiosurgery achieved 73.53% 5-year progression-free survival in a small postoperative papillary craniopharyngioma cohort.
Planning computed tomography radiomics predicted recurrence in human papillomavirus-positive oropharyngeal cancer
A multi-regional clinical-radiomics model reached an external-test area under the curve of 0.908 for 5-year recurrence prediction.
Magnetic resonance imaging radiomics model stratified survival risk after Gamma Knife for brain metastases
A multimodal imaging, radiomics, and clinical deep learning model showed moderate external validation for survival risk after Gamma Knife radiosurgery.
Perioperative immunotherapy with chemoradiation showed encouraging response in resectable gastric and gastroesophageal junction cancer
A single-arm phase 1/2 trial reported a 39.1% pathologic complete response rate among resected patients, with grade 4 toxicities in 10%.
Hydrogen gas inhalation showed exploratory metabolic and toxicity signals during head and neck chemoradiotherapy
Adjunctive hydrogen gas inhalation was associated with numerically fewer moderate toxicities and exploratory serum metabolomic changes during head and neck chemoradiotherapy.
Single-fraction radiotherapy matched multifraction treatment for malignant bone tumor pain
Single-fraction external beam radiotherapy provided similar pain relief to multifraction treatment in this meta-analysis of malignant bone tumor pain.