CT-guided online adaptation improved prostate SBRT dosimetry
CT-guided online adaptive prostate SBRT was feasible, with adapted plans selected in 95% of fractions and dosimetric improvements in 85%.
Latest research
Search the archiveConcurrent polatuzumab vedotin and radiotherapy showed no unexpected toxicity in B-cell lymphoma
Concurrent polatuzumab vedotin and radiotherapy was feasible in heavily pretreated aggressive B-cell lymphoma without unexpected acute or subacute toxicity.
Twice-weekly 28 Gy whole-breast irradiation showed low toxicity in early breast cancer
Twice-weekly 28 Gy in 5 fractions produced no grade 3 or higher toxicity and 98.8% excellent-to-good cosmesis at 1 year.
NEOTRAC shortened treatment duration without improving pCR in HER2-positive inoperable breast cancer
Concurrent neoadjuvant radiotherapy shortened treatment duration but did not improve pathological complete response or survival.
Timing shaped radiotherapy-immunotherapy synergy across mechanisms
This systematic review found that optimal radiotherapy-immunotherapy sequencing depends on the immune mechanism being targeted.
VMAT lattice SFRT was deliverable across Edge and Halcyon linacs
VMAT-based lattice SFRT achieved cross-platform deliverability with gamma pass rates above 90% and preserved peak-to-valley dose ratios.
MIM software accelerated sarcopenia screening during prostate radiotherapy planning
MIM-based skeletal muscle index measurement matched ImageJ while reducing processing time from 10 to 3.5 minutes.
Federated learning improved radiation pneumonitis prediction across lung cancer datasets
A center-specific federated learning model predicted grade 2 or higher radiation pneumonitis with stable cross-dataset performance.
Fat necrosis remained low after single-fraction stereotactic partial breast irradiation
Single-fraction GammaPod partial breast irradiation produced 12.1% fat necrosis and 4.1% symptomatic fat necrosis in a phase 2 trial.
Knowledge-based planning reduced organ-at-risk dose in head and neck and brain planning
RapidPlan reduced several organ-at-risk dose metrics while maintaining comparable target coverage in head and neck and brain radiotherapy planning.
Thoracic radiotherapy with atezolizumab increased toxicity in extensive-stage small cell lung cancer
TREASURE found no survival benefit and higher serious toxicity with thoracic radiotherapy added to atezolizumab maintenance.
Radiotherapy was tolerated without unexpected skin toxicity in epidermolysis bullosa
Four epidermolysis bullosa patients tolerated radiotherapy without greater-than-expected cutaneous toxicity, despite maximum skin dose up to 50.4 Gy.
Dutch survey found wide variation in radiotherapy for unresectable recurrent rectal cancer
Dutch radiation oncologists reported substantial variation in dose, delineation, and follow-up for unresectable locally recurrent rectal cancer.
Pencil-beam scanning proton re-irradiation showed low acute toxicity in recurrent head and neck cancer
Pencil-beam scanning proton re-irradiation achieved 17.2-month median survival with 7.7% grade 3 or higher oral mucositis.
SMART-BRAIN enabled proton-based non-target brain sparing in medulloblastoma planning
SMART-BRAIN proton planning spared portions of non-target brain while maintaining target coverage in five medulloblastoma cases.