FDG PET/CT improved nodal contour reproducibility over MRI in stage II–III breast cancer
Semi-automated FDG PET/CT produced more reproducible nodal target volumes than manual MRI and identified all metastatic nodes consistently.
Tag
Breast
Most breast cancer RT appears safe with ADCs, but T-DM1 raises concern after brain SRS
Across 3,817 patients, severe toxicity was uncommon with RT plus ADCs, except for a radiation-necrosis signal with intracranial RT and T-DM1.
Breast skin V40 predicted lymphedema after breast-conserving therapy
Skin V40 >90 cc nearly quadrupled breast lymphedema odds, while mammographic skin thickening provided an objective detection signal.
Cognitive engagement prolonged deep-inspiration breath-hold during breast radiotherapy
A simple counting task added about 19 seconds to prolonged DIBH in breast cancer patients after oxygenation and hyperventilation.
Multicatheter HDR partial-breast irradiation maintained low recurrence through 15 years
Four-day multicatheter HDR partial-breast irradiation produced 3.8% ipsilateral recurrence at 15 years with exclusively grade 1-2 recorded late toxicity.
Breast radiotherapy patients valued both animated video and printed education
Video and printed education performed similarly, while half of patients preferred video and self-reported anxiety fell from 30% to 5%.
SABR controls oligometastatic breast lesions well, but systemic benefit remains uncertain
SABR achieved 92.5% one-year local control in oligometastatic breast cancer, while pooled randomized evidence did not definitively establish a PFS benefit.
Late chest-wall pain affected one-third of patients after breast radiotherapy
Across 5,509 evaluable patients, 34% developed late chest-wall pain, although definitions and reported risk factors varied substantially.
DIBH workflow changes sharply reduced chest-wall motion during breast radiotherapy
Four quality-improvement measures reduced >3-mm chest-wall errors from 21.2% to 4.7%, but sternal marker placement increased skin reactions.
Virtual reality often reduced anxiety and pain during breast cancer care
Across 14 studies, 9 of 11 anxiety studies and 3 of 5 pain studies reported significant improvement with virtual reality.
SGRT-assisted DIBH reduced heart and LAD dose in left-sided breast radiotherapy
Across 52 studies, SGRT-assisted DIBH reduced mean heart dose by 1.21 Gy and LAD dose by 7.05 Gy versus free breathing.
Cardiac dose patterns and early ECG changes differed by breast cancer laterality
Left-sided breast IMRT was linked to more repolarization changes, while right-sided treatment produced predominantly rhythm abnormalities.
Iridium-192 remains the best-supported HDR source for breast brachytherapy
Iridium-192 has the strongest long-term breast brachytherapy evidence; cobalt-60 is dosimetrically comparable, while ytterbium-169 remains clinically unvalidated.
Five-fraction breast RT is established for WBI and APBI, while RNI evidence matures
Five-fraction RT is well supported for selected whole- and partial-breast treatment, while regional nodal and postmastectomy evidence remains less mature.
Sinoatrial node dose was linked to early ECG abnormalities after breast IMRT
Higher sinoatrial node low-dose exposure independently tracked with new ECG abnormalities after postoperative breast IMRT in this exploratory retrospective cohort.