Low incidental brain doses were not linked to early cognitive decline after head and neck radiotherapy
Regional brain dose showed no significant association with cognition through 12 months, although only 24 patients completed one-year testing.
Tag
late-effects
Prostate radiotherapy modestly increased secondary pelvic cancer incidence over long follow-up
Randomized evidence suggested a 4.5-point increase in second-cancer incidence, while excess mortality from other cancers was substantially smaller.
Pelvic radiotherapy was associated with modest excess secondary uterine cancer risk
Twenty-year secondary uterine cancer incidence increased after pelvic radiotherapy, but absolute excess risk remained below two percentage points.
Severe late toxicity was generally uncommon after prostate radiotherapy in REQUITE
Across 1,760 patients, most grade 3 adverse events remained below 1.5%, although post-prostatectomy urinary incontinence reached 10.2% by eight years.