Prostate target expansion identified fractions most likely to benefit from online re-optimization
Without online re-optimization, 65.3% of prostate fractions missed 95% target coverage, with later target expansion strongly linked to coverage loss.
Tag
online-adaptive
On Ethos, intensity-modulated radiotherapy generated faster and spared several pelvic organs better than arc therapy
Nine-field intensity-modulated radiotherapy shortened overall planning-plus-delivery time and improved several pelvic dose metrics compared with volumetric modulated arc therapy.
Daily adaptation supported 17-fraction definitive chemoradiotherapy for cervical cancer
Daily online adaptation improved pelvic target coverage during 17-fraction cervical chemoradiotherapy, with 10% grade ≥3 gastrointestinal toxicity.
Simulation-free CBCT workflow enabled urgent radiotherapy within about two hours
The OSCAR workflow delivered the first urgent or palliative fraction without planning CT in approximately 1 hour 50 minutes.
Simulation-free adaptive lung SBRT was feasible in the ONE STOP pilot
Eight of ten patients completed simulation-free single-fraction adaptive lung SBRT, with treatment taking a median 72 minutes.
Online proton adaptation improved dosimetry but required about one hour per fraction
Adaptation would have improved organ sparing or target coverage in 46% of fractions, with a median workflow time of 61.9 minutes.
Daily adaptation improved target coverage and rectal sparing in postoperative prostate radiotherapy
Daily adaptation increased prostate-bed coverage from 92.1% to 98.5% and reduced high-dose rectal exposure during hypofractionated salvage radiotherapy.
CT-guided online adaptation improved prostate SBRT dosimetry
CT-guided online adaptive prostate SBRT was feasible, with adapted plans selected in 95% of fractions and dosimetric improvements in 85%.
Rectal air did not compromise prostate online adaptive radiotherapy robustness
Rectal air or air-filled balloons did not cause clinically relevant dose increases when posterior tissue shifts stayed within 5 millimetres.
Feature-wise scanning network improved liver radiotherapy segmentation efficiency
Feature-wise scanning Mamba improved liver radiotherapy segmentation accuracy while reducing model size and inference time.
Daily adaptive prostate stereotactic body radiotherapy improved target coverage
Daily cone-beam computed tomography-based adaptation improved prostate stereotactic body radiotherapy target coverage, but organ-at-risk dose benefits were inconsistent.
Virtual magnetic resonance linear accelerator improved adaptive pelvic lymph node radiotherapy dosimetry
Daily magnetic resonance-informed adaptation increased target coverage by 14% and reduced bowel dose by 7% for pelvic lymph node metastases.
End-to-end test achieved high dosimetric agreement across adaptive platforms
A reusable phantom-based test verified simulation-omitted adaptive workflows on cone-beam computed tomography-guided and magnetic resonance-guided treatment systems.
Two-hour fasting did not reliably stabilize stomach volume during pancreatic stereotactic radiotherapy
Standardized two-hour fasting produced reproducible stomach volumes in only 42% of patients receiving magnetic resonance-guided pancreatic stereotactic radiotherapy.