Pencil-beam scanning proton re-irradiation showed low acute toxicity in recurrent head and neck cancer
Pencil-beam scanning proton re-irradiation achieved 17.2-month median survival with 7.7% grade 3 or higher oral mucositis.
Tag
Reirradiation
Hypofractionated proton reirradiation showed similar survival to photons in recurrent glioblastoma
Median survival was 8.3 months after proton reirradiation, with 5.6% grade 3–4 radiation necrosis and no survival difference versus photons.
ESTRO–ASTRO guidance standardises reirradiation for locally recurrent rectal cancer
ESTRO–ASTRO guidance supports selected rectal cancer reirradiation using 30–40 Gy regimens, cumulative dose assessment, inverse planning and daily volumetric imaging.
Proton reirradiation achieves high locoregional control in recurrent breast cancer
Pencil-beam proton reirradiation for locoregional breast cancer recurrence achieved 95% three-year overall survival, with severe toxicity uncommon despite a 21% rib-fracture rate.