RapidPlan lung SBRT model used gEUD objectives for reproducible planning
A RapidPlan lung SBRT model generated clinically acceptable plans in 52% of validation cases on first optimization.
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sbrt
CT-guided online adaptation improved prostate SBRT dosimetry
CT-guided online adaptive prostate SBRT was feasible, with adapted plans selected in 95% of fractions and dosimetric improvements in 85%.
Artificial intelligence surrogate estimated coronary artery dose in lung stereotactic body radiotherapy
An artificial intelligence coronary artery surrogate strongly correlated with manual dose metrics in simulated lung stereotactic body radiotherapy.
Immuno-Eclipse radiotherapy controlled bulky tumor models through antitumor immunity
Immuno-Eclipse radiotherapy improved bulky tumor control in mice through natural killer and cytotoxic T-cell immunity.
Daily adaptive prostate stereotactic body radiotherapy improved target coverage
Daily cone-beam computed tomography-based adaptation improved prostate stereotactic body radiotherapy target coverage, but organ-at-risk dose benefits were inconsistent.
Magnetic resonance imaging after hepatocellular carcinoma stereotactic body radiation therapy requires serial assessment
After stereotactic body radiation therapy for hepatocellular carcinoma, magnetic resonance response evolved over months, making early enhancement alone unreliable.
Carbon fiber-reinforced implants may reduce uncertainty in postoperative spine stereotactic body radiotherapy
Carbon fiber-reinforced polyetheretherketone implants consistently reduced imaging artifacts and dosimetric uncertainty versus titanium, but clinical outcome evidence remains limited.
Early stereotactic radiotherapy was associated with longer progression-free survival in pancreatic cancer
Adding early stereotactic body radiotherapy to neoadjuvant chemoimmunotherapy was associated with median progression-free survival of 12.5 versus 6.6 months.
DGMP toolkit finds no single method sufficient for stereotactic radiotherapy quality assurance
No single patient-specific quality assurance method covered all stereotactic radiotherapy risks, supporting combinations of measurement, independent calculation, imaging, and monitoring.
Regional lymph node irradiation altered immune responses after sinonasal stereotactic radiotherapy in dogs
Regional lymph node irradiation was linked to attenuated local cytokine shifts and nodal damage and cell-death signatures after sinonasal stereotactic radiotherapy.
Off-axis beam optimization reduced lung dose in posterior lung stereotactic body radiotherapy
Off-axis beam optimization preserved target coverage while reducing lung dose and enabling collision-free beam geometry for posterior lung lesions.
Split inhale–exhale planning reduced rib dose in lung stereotactic body radiotherapy
Splitting eight fractions between inhale and exhale breath-holds reduced maximum rib dose from 67.9 to 33.5 Gy without compromising target coverage.
Failure analysis identifies target definition and motion management as key risks in stereotactic arrhythmia radioablation
Multimodal registration, motion management, and arrhythmia substrate definition were the highest-risk steps in stereotactic arrhythmia radioablation.
Commercial lung phantom density errors can reduce target coverage by 3%
Lot-to-lot density variation in lung-equivalent inserts reduced planning target volume coverage by up to 3%, exceeding the stated clinical tolerance.
Single-fraction prostate radiotherapy achieved 92.9% three-year biochemical relapse-free survival
A single 19-Gy fraction achieved 92.9% three-year biochemical relapse-free survival with limited grade 2 gastrointestinal and genitourinary toxicity.