Second malignancy risk reached 6.7% at 15 years after IMRT for nasopharyngeal cancer
Among long-term NPC survivors treated with IMRT, radiation-related second malignancy incidence reached 6.66% at 15 years.
Tag
secondary-malignancy
Low-dose radiotherapy showed very low in-field solid cancer incidence after musculoskeletal treatment
Only three in-field solid malignancies occurred among 4,699 patients, while marrow-adjacent irradiation was associated with slightly more hematologic malignancies.
Pelvic radiotherapy was associated with modest excess secondary uterine cancer risk
Twenty-year secondary uterine cancer incidence increased after pelvic radiotherapy, but absolute excess risk remained below two percentage points.
Circadian disruption may modify radiation-induced acute myeloid leukaemia risk
Circadian dysregulation could impair DNA repair and haematopoietic control after radiation exposure, but direct evidence linking it to acute myeloid leukaemia is lacking.
Partial breast irradiation projected lower secondary lung cancer risk than whole breast irradiation
Partial breast irradiation projected lower lifetime secondary lung cancer risk than whole breast irradiation in Korean early-stage breast cancer cohorts.