End-to-end test achieved high dosimetric agreement across adaptive platforms
A reusable phantom-based test verified simulation-omitted adaptive workflows on cone-beam computed tomography-guided and magnetic resonance-guided treatment systems.
A reusable phantom-based test verified simulation-omitted adaptive workflows on cone-beam computed tomography-guided and magnetic resonance-guided treatment systems.
CyberKnife improved conformity and reduced cardiac, pulmonary, and low-dose exposure, while noncoplanar linac techniques remained clinically acceptable alternatives.
A conventional-fractionation model produced clinically acceptable moderately hypofractionated prostate plans, with comparable overall quality and slightly reduced target homogeneity.
Lot-to-lot density variation in lung-equivalent inserts reduced planning target volume coverage by up to 3%, exceeding the stated clinical tolerance.
Discrete pulse counts limited fractional monitor unit precision, particularly for high-dose-per-pulse flattening filter-free beams.
Hydrogen peroxide production decreased as proton dose rate increased, with Geant4-DNA simulations reproducing the oxygen-dependent experimental trend.
Patient-specific surface imaging reconstructed breast radiotherapy dose with a 93.8% gamma passing rate and 42-millisecond latency without additional imaging radiation.
Reference datasets can support linear accelerator beam modelling, but machine-specific measurements remain essential for small fields, complex delivery, and long-term verification.
Prompt-gamma profiles tracked beam range, but stronger neutron backgrounds reduced retrieval precision for carbon ions under clinically relevant conditions.
Measured multi-energy extraction characteristics enabled accurate delivery-time prediction across 605 clinical proton fields, supporting more reliable interplay simulations.
Anatomy- and dose-based machine learning predicted gamma passing rates accurately for organs at risk, but less reliably for target volumes.
Dynamic collimation improved target-region contrast and signal-to-noise ratio while preserving full-field information without increasing the total photon budget.
Semi-automated trajectory planning reduced workflow time and needle use while maintaining clinically acceptable target coverage and organ-at-risk doses.
A reusable positioning pouch displaced the genitalia from the treatment field while receiving high satisfaction ratings from patients and radiation therapists.
Four-dimensional prompt-gamma imaging detected clinically relevant proton range shifts associated with anatomical change during pancreatic proton therapy.