STAMP accelerated gynecologic brachytherapy planning without compromising dosimetry
The standardized workflow generated clinically comparable interstitial brachytherapy plans in a median of 10 minutes versus 28 minutes for manual planning.
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technical-relevance
Online proton adaptation improved dosimetry but required about one hour per fraction
Adaptation would have improved organ sparing or target coverage in 46% of fractions, with a median workflow time of 61.9 minutes.
Carbon-ion Gy(RBE) values are not directly interchangeable between planning systems
Different carbon-ion RBE models can assign substantially different biological doses to the same absorbed-dose distribution, requiring context-specific translation.
Submillimetre MLC errors substantially altered HyperArc brain metastasis dose
A 1 mm symmetric MLC closing reduced minimum GTV dose by 25%, while translations caused cumulative target undercoverage.
High-density bolus provided accurate superficial photon dose when air gaps were minimized
A 1 cm high-density bolus overcame 6 MV photon build-up, but a 2 cm air gap reduced small-field skin dose by 21%.
TLD-100 response varied systematically with synchrotron proton dose rate
TLD-100 over-responded below 7 Gy/s and under-responded above 300 Gy/s, despite remaining dose-independent from 3 to 18 Gy.
T1-weighted MRI plus CT best automated EPTN neuro-oncology organ contouring
A dual-input MRI–CT model segmented 25 neurological organs with a median Dice score of 0.80 and surface Dice of 0.84.
Protons produced greater subclinical lung changes after breast nodal irradiation
Proton therapy produced greater CT-detected lung changes than photons despite lower lung dose and no increase in clinical pulmonary toxicity.
Fifteen years of radiotherapy data were converted into an AI-ready resource
An open-source workflow structured 15 years of radiotherapy data, although reirradiation prediction showed only modest discrimination.
Dose-guided positioning optimized proton target coverage within three minutes
Automated dose-guided positioning matched anatomical alignment overall and improved primary target coverage by 1.0% when the clinical goal was initially missed.
Transformer dose engine achieved near-Monte Carlo accuracy for carbon ion therapy
The Transformer calculated carbon-ion pencil-beam doses in 14 milliseconds with 98.0% gamma agreement at stringent 1%/1 mm criteria.
NanOx incompletely predicted laryngeal cancer cell survival across a helium Bragg peak
NanOx predictions differed from measured laryngeal cancer cell survival by 20–37% and overestimated the distal biological gradient.
Tomotherapy improved lung sparing in whole-pleural irradiation for disseminated thymic tumors
Tomotherapy improved target coverage and reduced bilateral lung exposure compared with VMAT and fixed-field IMRT in 20 whole-pleural irradiation cases.
Automated lattice radiotherapy evaluation cut analysis time nearly eightfold
An Eclipse-based tool reduced lattice plan evaluation from 15.4 to 2.0 minutes while maintaining close agreement with manual measurements.
Respiratory gating reduced lung SBRT target volumes and normal-tissue dose
A 30–70% gating window reduced planning target volume by 34% and mean lung dose by 0.75 Gy without compromising coverage.