Dutch survey found wide variation in radiotherapy for unresectable recurrent rectal cancer
Dutch radiation oncologists reported substantial variation in dose, delineation, and follow-up for unresectable locally recurrent rectal cancer.
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Pencil-beam scanning proton re-irradiation showed low acute toxicity in recurrent head and neck cancer
Pencil-beam scanning proton re-irradiation achieved 17.2-month median survival with 7.7% grade 3 or higher oral mucositis.
Gamma Knife radiosurgery showed durable control in postoperative papillary craniopharyngioma
Gamma Knife radiosurgery achieved 73.53% 5-year progression-free survival in a small postoperative papillary craniopharyngioma cohort.
Surface-guided radiotherapy supported frog-leg vulvar treatment setup
Surface-guided radiotherapy kept mean setup shifts near zero during frog-leg vulvar volumetric modulated arc therapy.
Thermo-optical surface guidance supported breast deep inspiration breath-hold radiotherapy setup
Thermo-optical surface monitoring with X-ray correction kept breast deep inspiration breath-hold setup errors within clinical tolerance.
Higher ovarian dose was linked to ovarian insufficiency after transposition in cervical cancer
All patients receiving more than 8 Gy mean dose or 16 Gy maximum dose to the least exposed ovary developed premature ovarian insufficiency.
Boswellia serrata was associated with acute kidney injury during radiation necrosis treatment
A case report linked high-dose Boswellia serrata use for radiation necrosis with reversible acute kidney injury.
A risk score predicted prolonged radiotherapy completion in locally advanced cervical cancer
A score above seven identified patients with treatment beyond 56 days in 53.6% versus 17.8% at lower scores.
Pan-mucosal irradiation did not improve outcomes in head and neck unknown primary cancer
Adding pan-mucosal irradiation did not improve survival or reduce mucosal recurrence compared with nodal-only irradiation in thoroughly staged head and neck unknown primary cancer.
Hypofractionated proton reirradiation showed similar survival to photons in recurrent glioblastoma
Median survival was 8.3 months after proton reirradiation, with 5.6% grade 3–4 radiation necrosis and no survival difference versus photons.
Proton therapy timing was not independently associated with worse rhabdomyosarcoma outcomes
Four-year overall survival was 81.2%, and starting proton therapy at week 14 or later was not independently associated with worse outcomes.
Carbon ion radiotherapy yielded 82.9% two-year locoregional control in stage III non-small cell lung cancer
Carbon ion radiotherapy achieved 82.9% two-year locoregional control, while combined immunotherapy was associated with longer overall survival.
Radiotherapy was associated with longer survival in metastatic cervical cancer
Adding radiotherapy to systemic treatment was associated with longer overall and progression-free survival without significantly higher acute toxicity.
No isolated failures in omitted nodal regions with reduced elective irradiation for early oropharyngeal cancer
Definitive intensity-modulated radiotherapy alone achieved 93.0% three-year overall survival, with no recurrence solely within omitted prophylactic nodal regions.
Mid-treatment tumour shrinkage predicted survival in oropharyngeal cancer
Tumour volume reduction above 40% during radiotherapy was independently associated with improved overall survival in patients with oropharyngeal cancer.