Higher LINAC SRS dose rate was linked to longer pain control in trigeminal neuralgia
Treatment failure at one year was 14.4% at 2400 MU/min versus 42.7% at 800 MU/min, with similar facial numbness.
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Kidney doses below QUANTEC limits still tracked with chronic kidney disease after para-aortic RT
Seven-year stage 3B CKD rose from 0% below 5 Gy mean kidney dose to 26.4% at ≥10 Gy.
Baseline urinary symptoms predicted late GU toxicity after hypofractionated prostate RT
Each one-point increase in baseline IPSS independently increased the odds of late grade ≥2 GU toxicity by 11%.
36.25 Gy/5 showed similar five-year control to 40 Gy/5 in prostate SBRT
After propensity matching, five-year PSA recurrence-free survival was 94.5% with 36.25 Gy versus 93.2% with 40 Gy.
ctDNA clearance after palliative RT tracked longer survival in advanced melanoma
One-year survival was 83% after ctDNA clearance versus 21% when ctDNA increased after RT during immune checkpoint inhibition.
Interstitial brachytherapy achieved 94% local control in complex non-melanoma skin cancer
Definitive interstitial or hybrid brachytherapy controlled 94% of difficult BCC/SCC lesions, although 8% developed grade 3–4 late toxicity.
SRS target location changed pain-response patterns in trigeminal neuralgia
Distal targeting produced more overall pain relief, while proximal targeting yielded more complete pain freedom and medication discontinuation.
Overfilling the bladder made prostate radiotherapy longer and more frustrating
Bladder diameter >10 cm at simulation was associated with longer fractions, more interruptions and greater patient frustration during prostate RT.
Comorbidity mattered more than chronological age after proton therapy for hepatocellular carcinoma
Age ≥75 did not independently predict outcomes after proton therapy for HCC, while CCI ≥3 was associated with more than threefold higher mortality.
Cardiac dose patterns and early ECG changes differed by breast cancer laterality
Left-sided breast IMRT was linked to more repolarization changes, while right-sided treatment produced predominantly rhythm abnormalities.
Ultracentral lung SBRT produced more grade 3 toxicity than central SBRT
Grade 3 toxicity was 16.7% for ultracentral versus 8.7% for central lung tumors, with no grade ≥4 events in this real-world cohort.
Metastasis-directed EBRT was feasible alongside Lu-PSMA-617 in metastatic prostate cancer
Among 88 patients receiving both treatments, PSA50 response was 55.7% and prior metastasis-directed EBRT did not increase hematologic toxicity.
Integrated rapid palliative RT achieved fast treatment without a dedicated clinic
A routine departmental workflow delivered rapid palliative RT with a median 109-minute treatment process despite having no dedicated rapid-access clinic.
Sinoatrial node dose was linked to early ECG abnormalities after breast IMRT
Higher sinoatrial node low-dose exposure independently tracked with new ECG abnormalities after postoperative breast IMRT in this exploratory retrospective cohort.
Four-point symptom score identified radiation pneumonitis in older lung cancer patients
In POLCAR, a four-point symptom threshold detected seven of eight pneumonitis cases and achieved a 97% negative predictive value.