Salvage proton therapy achieved durable control after prostate cryotherapy or HIFU failure
Ten-year biochemical control was 64.7% after salvage proton therapy, with 3.2% late grade 3 genitourinary toxicity.
Latest research
Search the archiveDaily low-dose cisplatin chemoradiotherapy remained feasible in older stage III NSCLC
Patients >70 receiving 66 Gy with daily low-dose cisplatin had survival and severe toxicity similar to younger patients in this retrospective cohort.
Cardiac avoidance area dose was associated with survival after oesophageal radiotherapy
Maximum cardiac avoidance area dose below 43.5 Gy was associated with longer median survival after curative-intent oesophageal radiotherapy.
Locoregional radiotherapy was associated with longer survival in de novo metastatic HNSCC
In de novo metastatic HNSCC, locoregional radiotherapy and first-line immunotherapy were independently associated with longer overall survival.
Trismus persisted in 35% of head and neck cancer survivors 10 years after radiotherapy
Ten years after radiotherapy, 35% of long-term head and neck cancer survivors had trismus with persistently worse quality of life.
Coronary intravascular brachytherapy prolonged restenosis-free intervals after recurrent in-stent restenosis
Median restenosis-free interval increased from 96 to 350 days after intravascular brachytherapy for repeatedly recurrent coronary in-stent restenosis.
Upright pediatric radiotherapy roadmap prioritizes anesthesia safety and prospective validation
A multidisciplinary roadmap defines the safety, imaging and research requirements needed before upright radiotherapy can be adopted more broadly in children.
Older patients maintained recurrence control after definitive anal cancer chemoradiotherapy
Patients aged ≥70 had similar recurrence outcomes after definitive chemoradiotherapy despite inferior overall survival and greater competing mortality.
Benzydamine spray reduced severe mucositis in a randomized head and neck pilot
Grade ≥3 mucositis at week 6 occurred in 11.1% with benzydamine versus 70.6% with standard care.
Five-parameter model reproduced physician-specific glioma CTV contouring patterns
In 93 glioma cases, a five-parameter CTV model reproduced physician contours and achieved similar blinded clinical quality ratings.
International consensus standardizes 3D target volumes for low-dose RT of tendinitis and bursitis
IBTVG experts defined reproducible CT-based GTV, CTV and PTV concepts for common tendinitis and bursitis sites treated with low-dose radiotherapy.
Paediatric radiotherapy access improved globally, but major disparities persist
A decade after the previous IAEA survey, access to modern paediatric radiotherapy improved, but substantial technology, imaging and workforce disparities remain.
ESTRO and ILROG define modern technical standards for total skin electron therapy
ESTRO consensus recommendations establish standardized dose, delivery, shielding and quality-assurance principles for total skin electron therapy.
Dose accumulation was feasible for toxicity assessment in MR-guided abdominal SABR
Accumulated gastrointestinal doses were generally lower than planned, while higher small-bowel dose showed exploratory associations with diarrhoea after MR-guided SABR.
Machine learning showed moderate external prediction of hypothyroidism after head and neck radiotherapy
Random forest reached external AUC 0.769 for 12-month radiation-induced hypothyroidism, but calibration and clinical utility weakened outside the development center.