SGRT reduced pelvic pitch and longitudinal setup errors in vulvar radiotherapy
In 20 vulvar cancer patients, SGRT reduced pitch error from 1.21° to 0.07° and longitudinal error from 4.9 to 0.4 mm.
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Helium pencil beam commissioning achieved submillimetre range accuracy and robust dose agreement
A scanned helium beamline achieved submillimetre range accuracy and generally ≤3% dose agreement, supporting further translation toward clinical helium therapy.
Cardiac-dose model validated non-cancer death risk in one lung SBRT cohort
The model calibrated well only when non-cancer death was defined consistently; an overall-survival version validated in both external cohorts.
Patient-specific 3D-printed templates enabled efficient brachytherapy for complex cervical cancer
Template-guided implantation achieved a median HR-CTV D90 of 92.9 Gy with low severe toxicity across 555 brachytherapy fractions.
Nationwide play-based programme helped children engage with paediatric radiotherapy
The programme prepared 256 children for radiotherapy and was associated with avoidance of daily general anaesthesia in five selected cases.
Adaptive MR-guided prostate SBRT showed low toxicity after the early treatment peak
Grade ≥2 urinary toxicity fell from 22% at two weeks to 3% at six months, with almost no clinically significant bowel toxicity.
Prostate radiotherapy biomarker review found timing more limiting than assay choice
None of four selected blood-biomarker domains currently supports treatment personalization, and sampling schedules frequently failed to match expected biological kinetics.
Virtual reality increased confidence after HDR prostate brachytherapy training
Brief virtual-reality training increased self-reported procedural confidence, but knowledge, technical skill, retention, and clinical performance were not tested.
Protons reduced spinal cord and bowel dose in single-fraction spine SBRT plans
Proton plans preserved 20-Gy target coverage while reducing spinal cord, oesophageal, lung, and bowel dose compared with photon VMAT.
Combined dose–LET model predicted temporal lobe necrosis after skull-base proton therapy
Temporal lobe volumes receiving high dose or moderate dose with high LET jointly predicted grade 2 or higher necrosis.
BARitOne will escalate oropharyngeal dose only for MRI-defined non-responders
BARitOne uses on-treatment diffusion MRI to increase gross tumour dose from 65 to 73 Gy only in predicted non-responders.
Five-fraction MR-guided prostate-bed radiotherapy showed low early toxicity
No grade 3 toxicity occurred after five-fraction MR-guided salvage radiotherapy, while urinary and bowel quality-of-life scores remained stable.
Anal cancer radiotherapy–immunotherapy trials remain too heterogeneous for direct comparison
Twelve trials used 14 immunotherapy regimens with major differences in eligibility, radiotherapy, chemotherapy, endpoints, and translational analysis.
Prostate radiotherapy modestly increased secondary pelvic cancer incidence over long follow-up
Randomized evidence suggested a 4.5-point increase in second-cancer incidence, while excess mortality from other cancers was substantially smaller.
Abdominal airbag matched plate compression but increased lateral setup error
Airbag compression reduced upper-abdominal respiratory motion comparably to a rigid plate but produced larger left–right setup errors.