Action-priority FMEA narrowed radiation therapy QA risks from 30 to seven
A severity-weighted action-priority framework identified the same seven highest RT workflow risks while avoiding 23 additional traditional FMEA flags.
Latest
OPT-former enabled near-real-time automated eye tracking during ocular proton therapy
OPT-former matched a three-network segmentation pipeline while processing eye images 2.6 times faster and improved further with patient-specific fine-tuning.
AI is moving across particle therapy planning but clinical validation remains the bottleneck
AI can automate particle planning, dose prediction, adaptation and quality assurance, but limited data and validation still constrain clinical adoption.
uTPS produced deliverable Halcyon VMAT plans comparable with Eclipse
uTPS generated Halcyon VMAT plans with generally comparable dosimetry to Eclipse and greater than 97% gamma passing rates.
ALTJ V35Gy above 50% tripled lymphedema risk after breast radiotherapy
Irradiating more than half of the axillary-lateral thoracic junction to 35 Gy was independently associated with a threefold higher lymphedema risk.
Dose–LET hotspots were associated with capsular contracture after proton postmastectomy radiotherapy
Combined high-dose and high-LET exposure around breast implants was associated with severe capsular contracture after proton postmastectomy radiotherapy.
OmicsMap improved CT-based distant metastasis prediction across head and neck cancer cohorts
Modeling relationships between CT radiomic features improved distant-metastasis prediction over conventional radiomics across independent head and neck cancer cohorts.
Multi-RBE LET optimization increased target LET by 29% in sacral chordoma
Multi-RBE carbon-ion optimization increased near-minimum GTV LET by 29.2% while maintaining conventional dose coverage and interfraction robustness.
Deep learning predicted distant metastasis from CT and dose in head and neck cancer
A model integrating planning CT, 3D dose and tumor contours achieved strong external prediction of distant metastasis but weaker local-recurrence performance.
Robust optimization minimized lung-dose trade-offs in carbon-ion planning for stage I NSCLC
Robust optimization improved target coverage with less lung-dose penalty than margin expansion, while density override was particularly useful for solid tumors.
Higher immune-cell radiation dose was associated with worse breast cancer-specific survival
Each 1-Gy increase in estimated immune-cell dose was associated with 66% higher breast cancer mortality after multivariable adjustment.
Nearly one-third of abdominal radiotherapy patients could not maintain planned DIBH
Despite successful simulation, 31.7% required DIBH gate modification or conversion to free breathing during abdominal radiotherapy.
Multimodal AI predicted radiation proctitis across different CT devices with 0.865 AUC
Combined radiomics, foundation-model and clinical features predicted grade ≥2 radiation proctitis with 0.865 AUC on an independent imaging device.
PTV coverage prescriptions poorly represented delivered tumor dose in lung SBRT
D95% and D98% PTV prescriptions produced substantial interpatient variability, while GTV- and ITV-based median or mean doses were more accurate.
Cervical cancer advanced by one stage approximately every 8.6 weeks before radiotherapy
Cervical cancer stage progression was estimated every 8.6 weeks of treatment delay and was faster among women living with HIV.