Insufficient ferroptosis promoted regulatory T-cell accumulation and radiotherapy resistance
Radioresistant tumors showed impaired ferroptosis and regulatory T-cell accumulation, while sorafenib enhanced the response to irradiation in mice.
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preliminary
FLASH radiotherapy reduced hepatic injury in a murine breast cancer model
FLASH radiotherapy preserved hepatic structure and metabolic homeostasis while maintaining tumor control in a preclinical breast cancer model.
Brain radiotherapy alone did not deplete circulating lymphocytes in a prospective cohort
Circulating lymphocyte counts remained stable during brain radiotherapy without concurrent chemotherapy, consistent with low estimated blood and cervical lymph-node dose