Radiotherapy 3D printing needs standardized quality assurance across institutions
Inter-centre material variability supports shared QA datasets and standardized acceptance criteria for clinical radiotherapy 3D printing.
Latest
Euro-EWING99 long-term analysis defines outcomes in 3,395 patients with Ewing sarcoma
Five-year progression-free and overall survival were 55.4% and 64.6%, with metastatic status and histologic response remaining major prognostic factors.
Surface monitoring detected clinically relevant motion in head and neck radiotherapy
SGRT triggered verification in 15% of head and neck fractions, but almost half of alerts were not confirmed on X-ray imaging.
Patient-reported neck fibrosis showed dose–response relationships after definitive head and neck radiotherapy
Dose to neck skin, subcutaneous tissue, and sternocleidomastoid muscle predicted fibrosis burden in nonsurgical head and neck cancer survivors.
Preoperative radiotherapy accompanied functional improvement after revision surgery for knee arthrofibrosis
Range of motion improved by nearly 29° after revision arthroplasty preceded by 8 Gy, with parallel improvements in pain and function.
More hypofractionated carbon-ion therapy increased sacral fractures without improving survival
Carbon-ion schedules produced similar tumour outcomes, but sacral insufficiency fractures occurred in 47% versus 24% with 4 Gy(RBE) fractions.
Empty-bladder prostate SBRT met the EMPTY-RT acute safety endpoint
Empty-bladder SBRT was feasible in 85% of screened patients, with grade 2 or higher urinary toxicity of 28.1%.
Escalating esophageal chemoradiotherapy from 50.4 to 60 Gy provided no benefit
Three-year outcomes numerically favored 50.4 Gy over 60 Gy, while multivariable analysis found no significant survival advantage from either dose.
Hypofractionated SIB reduced acute dermatitis in the randomized HYPOSIB trial
Grade 2 dermatitis fell from 38.6% to 25.3% with 16-fraction whole-breast radiotherapy plus simultaneous integrated boost.
4DCT ventilation accurately predicted lung function after cancer resection
4DCT ventilation predicted postoperative FEV1, FVC, and DLCO with concordance coefficients of 0.88–0.91 in the LIME trial.
CT–MRI fusion improved contrast-free lung perfusion mapping for radiotherapy planning
Multimodal CT–MRI perfusion maps matched SPECT better than single-modality methods and reduced high-function lung dose in exploratory planning.
STAMP accelerated gynecologic brachytherapy planning without compromising dosimetry
The standardized workflow generated clinically comparable interstitial brachytherapy plans in a median of 10 minutes versus 28 minutes for manual planning.
SBRT controlled bone lesions but rarely delayed systemic therapy in bladder cancer
Two-year local control reached 88%, but median progression-free survival was 5.8 months and systemic treatment changed after 4.4 months.
Re-irradiation was associated with longer survival after pediatric diffuse midline glioma progression
COMPPARE enrolled 2,524 patients from 51 institutions in 52 months, with Black participation reaching 16% of the cohort.
Poor sleep and fatigue were common after head and neck radiotherapy
Poor sleep affected 69% of survivors, while 21.4% screened as high risk for obstructive sleep apnoea.